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Comment by ctoa

8 hours ago

"A lot fatalities due to taking after hangovers" no, that's not how acetaminophen fatalities happen. In fact, the article you cited specifically mentions "there is no scientific evidence that people with AUD (alcohol use disorder) who take the recommended dose of acetaminophen increase their risk of liver damage."

Fatalities happen basically from: product stacking combination medicines people don't realize contain acetaminophen and/or multi-day accumulation exceeding max daily limit over multiple days.

Chronic drinkers have impaired acetaminophen processing so they can't handle otherwise safe doses, but fatalities still typically occur in multi-day accumulation scenarios. Their safe daily max is ~half that of a non drinker.

The effects of one round of acute drinking don't impair the liver in the same way. People are not dropping dead because they took a normal dose of acetaminophen for a hangover. Not that I'm recommending you start doing it, but it is a myth.

> Fatalities happen basically from: product stacking combination medicines people don't realize contain acetaminophen and/or multi-day accumulation exceeding max daily limit over multiple days.

I find it obnoxious that NyQuil has taken over as the default brand people grab for cough syrup, for that reason. It has acetaminophen, while Robitussin or such have the other active ingredients without that risk.

The typical person doesn't read and understand active ingredients, and it's lucky if they even check dosage instructions.

  • I absolutely think we should ban acetaminophen in otc combo meds. There was a big drop in hospitalizations when they dropped the max allowed dose in prescription drugs like Vicodin, there's no reason these otc things like NyQuil need to exist at all.

    • I think it's supposed to be an anti-abuse thing for commonly abused drugs.

      Maybe I'm crazy, but I don't think killing people is an improvement.