Comment by someothherguyy

in that paper, the author hypothesizes that these risks (based on the understanding of the biochemistry and animal experiments [0]), probably only appear when you consume a large amount of sugar (>1g/kg of fructose in that study), or when people use these fast absorbing sugars chronically (based on epidemiological surveys).

overall, it sounds like some of the concerns about sugar metabolism aren't necessarily buffered because you metabolize it faster or exercise more, but the evidence isn't really there to know anything much.

0. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)...