← Back to context

Comment by cj

6 hours ago

It sounds similar to Lipoprotein(a) blood test for cardiac risk.

It's (almost) purely determined by genetics. You can't do anything to improve it, other than to improve every other cardiac related risk factor.

(There are some experimental drugs in the pipeline, though)

There is an oral PCSK9 treatment (enlicitide) was recently released that provides a 30% reduction, and of course you can't get insurance coverage without the test. And there are 2 drugs with 90%+ reduction in Lp(a) in phase3 trials with expected release in 2027-8, in particular Olpasiran.