Comment by saghm

I feel like we just don't understand a lot about the human body still. Only a century and a half ago we had a US president die because a doctor rummaged around and damaged internal organs (with unwashed hands, because germ theory was still not uniformly accepted) to try to find a bullet on the wrong side of his body. We've come a long way since then, but it's not like we've been doing the field of medicine rigorously for all that long. The best strategy we have seems like pretty much the same as any other scientific field; come up with ideas based on what we know, try them out, and see if they work. That doesn't necessarily give us any actual insight into why it works though.