Comment by Amezarak
2 days ago
Leto II had visions of AI-driven Ixian hunter-killers annihilating all human life in the universe. That probably had something to do with it.
After the Scattering and the fulfillment of his eugenics program with the Siona gene, he no longer cares, because it is no longer possible for even AI to eradicate humanity.
His target was removal of prescience - which would have allowed that, AI or no AI.
In fact he also explicitly prepared a renewal of computing and thinking machines in order to break free from spacing guild
The Siona gene didn't actually remove prescience, it hid people from prescience. That's why Leto II is still able to control events as far in the future as Chapterhouse Dune.
This is an important distinction. It's also the case that Leto needed the Ixians for the no-ship technology, which he also regarded as of extreme importance for the same reason. Which also, remember, the Idaho gholas had to be confined to no-ships so they, lacking the Siona gene, wouldn't be visible to prescience.