Comment by JaRail

As far as SharePoint goes, the current versions should work just as well (usually better) in Chrome. Should be mostly on par since the 2013 release.

The biggest feature difference for SharePoint cross-browser has historically been with the ActiveX controls. Say you had Word installed, there was a control to open documents with Word. As in, you could click save/view/edit rather than just whatever the browser default was. Or with Skype, to see a user's available/busy/away status next to their name on a SharePoint page. So if you're looking at a wiki or calendar for something, you might go "oh, the author is free, I can just ask." Chrome's plug-in model was much stricter than ActiveX. That's why you'd see some features in IE but not Chrome.