Comment by kazinator

Lisp peaked very early, and grew at a voracious pace compared to progress in hardware. The result was that it required "big iron". Lisp was a victim of the same process that killed the mainframes: a rebooting of the computer industry with cheap, but (initially) under-powered microcomputers, to which legacy systems were not able to migrate.

There also arose a new generation of hackers brought up on the new microcomputers who didn't care for, know or else even have access to legacy systems. As microcomputers showed signs of advancement, old hackers who had learned how to make things fit into small memories 15 years prior brandished their skills, which popularized tools like Pascal and C. Turbo Pascal for MS-DOS PC's fit a compiler and IDE into under forty kilobytes.

In the 1980's, people who wanted to use their Lisp techniques to deploy into the microcomputer market were faced with rewrites. A blatant example of this is CLIPS: an expert system written in C which retains the Lisp syntax of its predecessor. https://en.wikipedia.org/wiki/CLIPS . CLIPS was inspired by a Lisp-based system called OP5. But that itself had also been rewritten into Bliss for speed: https://en.wikipedia.org/wiki/OPS5 .