Comment by dash2
3 years ago
But then I guess it is slightly less surprising that all 12 people had remission, rather than all 18. (Or if all 18 had remission, then that's amazing but might not be to do with the drug.) Maybe it is still a great result, just slightly less significant.
You're correct. We'd expect to see more extreme outcomes with smaller sample sizes. The question is does this translate to more drugs when administered early which was the real reason for this study.