Comment by yellowapple

There are plenty of examples of things being the other way around. For example, heavily modding Kerbal Space Program basically necessitated running Linux because that's the only platform that had a native 64-bit build that was even remotely stable (this has since been fixed, but for the longest time the 64-bit Windows version was horrendously broken) and therefore the only platform wherein a long mod list wouldn't rapidly blow through the 32-bit application RAM ceiling.