Comment by Hello71

> Wine isn't set up to support multiple installed versions of itself.

huh? the official wine packages for ubuntu, debian, and i believe fedora provide separate wine-devel and wine-staging packages, which can be installed in parallel with each other and with distro packages. in fact, debian (and ubuntu) as well as arch provide separate wine and wine-staging packages as part of the distro itself, no separate repo required.

wine has no special support for relocated installations, but no more or less so than any large Unix program; you can install as many copies as you want, but they must be compiled with different --prefixes, and you cannot use different versions of wine simultaneously with the same WINEPREFIX.