Comment by viraptor
2 years ago
https://sci-hub.hkvisa.net/10.1016/j.mehy.2013.11.018
While it discusses multi-year treatment, the paper says "After several weeks of such treatment the pattern of behavior in ADHD patients is normalized." which feels like something that could be easily tried out. Since it was published in 2013 I'd expect some follow-up? (checking for citations now)
Edit: Sadly, "No Tryptophan, Tyrosine and Phenylalanine Abnormalities in Children with Attention-Deficit/Hyperactivity Disorder" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777504/ 2016, larger study. (although they measure the amounts rather than ratios, so not exactly the same idea)
Nutritional studies are hard to get funding for in the first place, never mind the follow-ups.
They found nothing in the study, because IMI they were measuring the wrong neurotransmitters. Dopamine is not the cause of the symptoms. It has to do with glutamate and GABA Balance. Since stimulants can control effect glutamate and GABA as well as Dopamine , that’s why there is all the confusion.
B6 also plays a role in glutamate GABA balance through stimulating the glutamate dehydrogenase enzyme.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545734/
It looks like you have a whole stash of related papers. If you could send all those links, I'd really appreciate it.
They all stashed my brain after years of researching nutritional psychiatry.
As far as ADHD goes, I just suggest searching both PubMed and Google scholar for ADHD, glutamate and GABA.
I think glutamate and GABA play a larger, or fundenental role, in most psychiatric disorders.
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