Comment by tgtweak

More just this:

mke2fs -t ext4 -b 1024 -N 100000 -O ^has_journal,^uninit_bg,^ext_attr,^huge_file,^64bit [/dev/sdx]

(smaller block size, 100,000 inode file table entries (tuned to the number of blobs), no journal, no checksumming, no extended file attributes, use smaller integer file offset IDs, 32 bit padded vs 64 bit)

Then mount it and run the same test.

You could go even further and tune fopen BUFSIZE to be no greater than 12,000 bytes. You can even create this mount on a file inside your existing mount... which is essentially akin to having an sqlite file without needing a client library to read/write to it.

Anyway - if the purpose is to speed up reads and save disk space on small blob files, there is little need to ditch the file system and it's many many upsides.