Comment by giantg2

1 year ago

Not exactly. It establishes that error rates are high in those areas, demolishing the centarian numbers. It doesn't give much investigation into the averages at all. Where it does, it seems to compare adjusted numbers of one data set with unadjusted numbers of another. If you really want to get into the averages, you'd have to determine error rates and adjustments for each specific area, probably by jurisdiction or record keeper, and then compare them. The problem is, nobody is going through that process for the entire world so we just use the face value numbers until we want disprove a specific area and then compare the adjusted numbers against unadjusted numbers. The data is too massive to rigorously investigate. But this whole effort is moot. What tangible benefit comes from disproving blue zone data? These population level studies aren't meant to provide answers. They're meant to provide new variables. Each of the blue zone longevity recommendations have their own studies to either prove (food stuff) or disprove (drinking wine daily) them.

So yeah, it's great the errors in the data have been called out it's a bit surprising that the author interviewed is so angry in the article. I guess it's fitting that he got the Ig nobel, since this correction doesn't have any applicable impact to end result, which were additonal studies investigating the individual suggestions/variables, such as specific dietary practices.

If the error rates are high, there is no reliable signal that these areas are different, so how the hell can looking at their "new variables" help?

  • Go look up the studies that came out of it.

    It would be different if these were new studies, but this is all in the past. This new finding of unreliability doesn't have any impact, hence the Ig nobel instead of the real nobel.

There are basically zero studies which prove anything about particular foodstuffs. It's all observational studies with small effect sizes and multiple uncontrolled confounding variables: junk science.

We know we need certain essential nutrients to prevent deficiencies, an energy intake surplus causes weight gain, and a few substances like trans fat are problematic. Beyond that, people seem to be making claims and recommendations not backed by hard evidence and frequently confuse correlation with causation.

  • We aren't talking about unequivocal proof. If someone asks what they can do to increase longevity, it's perfectly reasonable to tell them about studies that show strong correlations and mention the way the confounding factors play a role.

    You might be interested to look into some of the twin studies that put twins on similar exercise regimens and differening diets. They seem to be the strongest evidence possible for this sort of thing. Hardly what I would call junk science.

    • The exercise part I can believe as we have somewhat better quality evidence there. But if you have seen dietary studies on twins that actually meet evidence-based medicine criteria then I would greatly appreciate a citation as those would be interesting to read.

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