Comment by seydor
6 months ago
this is such an interesting problem. Imagine expanding the input size to 3.2Gbp, the size of human genome. I wonder if previously unimaginable interactions would occur. Also interesting how everything revolves around U-nets and transformers these days.
You would not need much more than 2 megabases. The genome is not one contiguous sequence. It is organized (physically segregated) into chromosomes and topologically associated domains. IIRC 2 megabases is like the 3 sd threshold for interactions between cis regulatory elements / variants and their effector genes.
> Also interesting how everything revolves around U-nets and transformers these days.
To a man with a hammer…
Or to a man with a wheel and some magnets and copper wire...
There are technologies applicable broadly, across all business segments. Heat engines. Electricity. Liquid fuels. Gears. Glass. Plastics. Digital computers. And yes, transformers.
Soon we’ll be able to get the whole genome up on the blockchain. (I thought the /s was obvious)
Even just modeling 3D genome organization or ultra-long-range enhancers more realistically could open up new insights