Comment by emsign
4 days ago
Increasing the count and efficiency of mitochondria is gonna be a big deal. ME/CFS is caused by these organelles not working as they should.
4 days ago
Increasing the count and efficiency of mitochondria is gonna be a big deal. ME/CFS is caused by these organelles not working as they should.
Highly recommend red light therapy for this. There's a spreadsheet that contains [1] all the scientific research does on effect on mitochondria.
[1]: https://docs.google.com/spreadsheets/u/1/d/1ZKl5Me4XwPj4YgJC...
That’s a long list. Not all research is good research, or shows the effect you’re looking for. Where did this come from?
Do you use red light therapy? For what? How often? Where do you focus it? I did manage to get some red light masks although I find it hard to fit into my routine
Would also be interested in a routine that makes sense.
People use habit stacking or habit chaining to get it into their routines - helps me tremendously to make new things a daily habit.
But this depends on how often red light therapy might be actually helpful.
Isn’t simply getting enough outdoor sunlight just as good as red light therapy.
Yes, assuming you get exactly the right amount and somehow also never too much of the bad UV light. It's a finicky thing to get right, but bottom line yes.
Anyone interested in this should look up "MOTS-C" and "SS-31".
They're readily available online. Both of them are peptides that enhance mitochondrial function.
MOTS-C in particular is very fascinating.
I have a vial of 20mg I've yet to use.
I’m already getting a lot of (subjective) benefit from doing what I can with supplements that target each phase of the Krebs cycle’s bottlenecks, and glutathione production to delay ROS damage (which this paper finger-points at). My mental endurance to do things like program and handle corporate politics lasts hours longer on days when I do this.
Next I need to get a lot better cardio endurance but I have some pulmonary problems to deal with.
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
It’s not clear to me CFS is really a thing. To me it’s a catch all BS diagnosis that basically says “we don’t know what this is, so we’re calling it CFS”.
It is definitely a thing. It all fits with the mitochondria theory: after physical or mental exhaustion (increased metabolic turnover provided by mitochondria) the recovery time (sleep) for ME/CFS patients is increased to such a degree that normal daily tasks gets them into a energy low they can't recover from anymore.
Except there isn't any evidence of mitochondria problems in ME/CFS, even though a lot of studies have looked at them.
2 replies →
I mean, the S in CFS stands for "syndrome", which is "a set of medical signs and symptoms which are correlated with each others [...] When a syndrome is paired with a definite cause this becomes a disease." (From wikipedia.)
So I mean, yeah, that literally does mean "we don't know what this is, and we don't know what's causing it, so we're dumping everything that looks like it in a bucket while we do more research". But that doesn't mean it's not a real thing; it means that we don't know what it is or what's causing it (and that it may well not be a single thing at all).
That's pretty different than saying "it's not a thing at all".