Comment by chem83

Can confirm that Yubikey-like devices prevent the M1 MBP from fully sleeping, which eventually depletes the battery. My company's (big tech) IT department reached out to Apple's corp support and eventually got confirmation from Apple that they decided to close the issue w/o fix. Something to do with their USB controller's firmware, if memory serves.

Removing Yubikey before (or after) closing the lid completely prevents total battery drain for me.