Comment by w10-1

> More useful words are "negligible" and "problematic".

Yes, thank you! Worth emulating.

By comparison:

> A characteristic of these systems spanning so many orders of magnitude is that it is very frequently the case that one of the things your system will be doing is in fact head-and-shoulders completely above everything else your system should be doing, and if you have a good sense of your rough orders of magnitudes from experience, it should be generally obvious to you where you need to focus at least a bit of thought about optimization, and where you can neglect it until it becomes an actual problem.