Comment by entrox

Yes, it works basically everywhere you'd interact with a local file or directory.

For example, you open a remote dired buffer with C-x C-f /ssh:host:/dir/. Afterwards, opening a file or navigating to a directory will open it remotely as well. You can also use project functions or magit seamlessly. I have plenty of bookmarks remotely etc.

Fundamentally, you just prepend "/ssh:[user@]host:" to any path or file operation and things will magically Just Work (tm).