Comment by summa_tech

Would a SLG46880 work for you? It has 28 GPIOs, enough LUTs to make a 21-input OR gate, runs off 2.3-5.5V (two VCCIO partitions, but you can tie them together). It costs like a buck in 5k quantities - they used to be much cheaper when you bought them directly from Silego, but now that they've been acquired the price has been _improved_.

https://www.renesas.com/en/products/slg46880