Comment by shaneofalltrad

1 month ago

But cannabis the needs heat to convert, it’s more likely it evolved with Human influence considering the years of overlapping land races tied to our trade routes

THCa in cannabis plants is unstable. It will slowly convert to THC as it dries even at room temperature.

But CBD does not need heat to convert.

I have a hypothesis that taking cannabis (and especially CBD) out of our food chain may be contributing to the increase¹ in prevalence of chronic pain.

¹ https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_sourc...

  • THC comes in a plant in the THCa form. CBD comes in CBDa form.

    Both are not bioactive by default in their natural form.

    • All I'll say is go spend a day picking hops without gloves.

      There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form.

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      None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.

      2 replies →

    • Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.