Comment by dekhn

23&Me data is simply not accurate enough to make reasonable predictions about health outcomes.

I have a whole genome and nothing Google has built has been able to do anything useful with it, medically speaking. I could use DeepVariant to re-map all the raw reads, it would only slightly increase the accuracy of the estimate of my genome sequence. When I met with genetic counselors, they analyzed my genome and told me I had no known markers for any disease (and they also told me they Google all the unique variants that show up in the report).

(for what it's worth, I literally went to work at Google to improve their medical/health/genomics research, and after working on it a few years I concluded that the entire genomics field is about 90% fantasy. If you want actionable data, there are a small number of well-regulated tests that can help in a limited set of circumstances, but those aren't whole genome tests).