Comment by wtallis

It sounds like you're reasoning starting from an assumption that any claimed slowness of TCP would be something like a fixed per-packet overhead or delay that could be isolated and added back in to the result of your local testing to get a useful prediction. And it sounds like you think alternative protocols must be equally affected by latency.

But it's much more complicated than that; TCP interacts with latency and congestion and packet loss as both cause and effect. If you're testing TCP without sending traffic over real networks that have their own buffering and congestion control and packet reordering and loss, you're going to miss all of the most important dynamics affecting real-world performance. For example, you're not going to measure how multiplexing multiple data streams onto one TCP connection allows head of line blocking to drastically inflate the impact of a lost or reordered packet, because none of that happens when all you're testing is the speed at which your kernel can context-switch packets between local processes.

And all of that is without even beginning to touch on what happens to wireless networks.