Comment by greygoo222

5 hours ago

He is not using an LLM in some new and exciting way. The process of making a personalized mRNA vaccine looks something like this:

1. Collect and sequence patient's normal and tumor genomes 2. Predict immunogenic neoantigens from genome 3. Generate optimized mRNA sequence from neoantigens 4. Create vaccine from sequence

modulo some variations, which I wrote off the top of my head because I understand this technology.

Steps 1 and 4 are done by contracted labs. Steps 2 and 3 are doable through open-source computational tools and a little engineering. What does ChatGPT do here? ChatGPT explains the process, finds labs that will do 1 and 4 for pay, finds published algorithms and data for steps 2 and 3. It's barely more complicated than what ChatGPT would do to help a student with their homework.

Legal documents, on the other hand? Have you ever tried to get an LLM to do your taxes? It's not easy.

> Legal documents, on the other hand? Have you ever tried to get an LLM to do your taxes? It's not easy.

Taxes are numerate, which is where LLMs fuck up.

Legal documents are structured texts, which is where LLMs shine. Should you blindly trust the outcome? fuck no, but a good first pass is trivially achievable if you set the right parameters. and make sure its relevant to the right jurisdiction.