Comment by mleroy

Since you mentioned biohacking but are wary of "wetware" risks, consider Personal Bioinformatics via 30x Whole Genome Sequencing. Now that sequencing costs have dropped significantly, you can use AI to take a deep dive into the latest research surrounding your own genomic data.

While severall open medical databases and open-source tools exist, they are often fragmented or built for academia. There is significant room to contribute by hacking together better toolsets, localized databases, or AI-driven interfaces to make this data truly accessible.