Comment by matt-attack

7 days ago

This really needs to be done for a GLP-1 auto injecting needle.

Pretty sure it’s the same as an epi-pen as well.

It blows my mind. It’s a disposable, single use device that at the press of button:

1. Inserts the needle in your skin, 2. Slowly presses the plunger until the dose is injected 3. Then retracts the needle with plunger

Three distinct and seemingly opposing motions. With timing. All in a little plastic enclosure. It sure I can think of a toy with that kind of mechanism.

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matt-attack

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jaggederest  6 days ago

There's an even fancier mechanism with e.g. glucagon pens, where it actually has to rehydrate the freeze dried hormone (glucagon forms aggregations when it sits, has to be mixed fresh)

  • jaggederest  6 days ago

    Actually, after looking into it recently, this is actually not true any more. All the current glucagon delivery mechanisms are either dry powder or DMSO-based, so no actual water involved, and are premixed and ready to go basically the same as epipen style autoinjectors

    I'm excited for the advent of dasiglucagon which is a non-clumping peptide designed for the purpose.

spike021  6 days ago

When I was a kid I needed growth hormone shots. we used regular syringes that fit into this tan plastic "gun" thing. you pulled back the top into a locked position. placed the tip of the gun to the skin where the needle should inject, and pressed the trigger button to release the lock. can't remember if it also pushed the plunger though. this was back in the 90's.