Comment by wasmperson

One good example of DoD which isn't CPU-cache-related is relational databases. When designing a CRUD application, the Data-Oriented way of doing it is to figure out what data you will be storing and how to organize that data to minimize access times, which is what you're doing when you design the DB schema.

An example of failing to follow DoD is the N+1 query problem: a programmer builds an abstraction that operates on individual DB rows, but "where there's one, there's more than one": you will inevitably be running that code in a loop so that you can process multiple rows. If instead the programmer had abstracted over groups of rows, then per-item query overheads suddenly become per-batch overheads.