Comment by eru

My very own weightloss method is a lot simpler, and doesn't require anything beyond a trivial model of human metabolism:

Take your weight today as the start. Decide on your target weight.

Target trajectory := max(target weight, start weight - 100g * days passed since start)

Each day you check if you are above or below the target trajectory. If you are above, you fast. If you are are below, do whatever. (Where what 'whatever' means depends on your preferences. If you hate fasting, you can try to stay under the target trajectory, so you never hit the fasting fallback. If you don't mind fasting, feel free to eat cake on your 'below' days.)

No worries about genetics or metabolism etc needed. Produces a 100g a day reduction, if followed.