Comment by toomuchtodo

21 hours ago

CAR T-cell therapies (immunotherapy, tldr priming the immune system to respond)

https://www.cancer.gov/about-cancer/treatment/research/car-t...

https://www.cancer.gov/about-cancer/treatment/types/immunoth...

https://en.wikipedia.org/wiki/CAR_T_cell

https://www.theguardian.com/society/2026/may/10/cancer-treat...

https://hn.algolia.com/?dateRange=all&page=0&prefix=true&que...

CAR-T is not a cure in any sense of the word, in part because "cure" is just not a scientifically valid concept in oncology. I would know, CAR-T saved my life, but this was at great cost and is not even remotely close to a guarantee, and the side-effects can be beyond devastating https://news.ycombinator.com/item?id=49827669. At best, CAR-T is more like a tradeoff: often just a coin-flip's chance to live, for long-term—maybe even permanent—life-shattering consequences.