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Comment by robotsquidward

5 hours ago

- Enhances ANTI-tumor... sounds good - ANTI-tumor immunity... sounds bad? - Read first few paragraphs as a typical medical rube, got nowhere

So, creatine = good?

Don’t worry, if you aren’t confused enough there’s also this to send you through another cycle! https://pubmed.ncbi.nlm.nih.gov/33811821/

  • That link sent me into a neverending redirect and reCAPTCHA loop, so very confused.

    • He did say it's a cycle after all! Scnr

      Title:

      > Creatine promotes cancer metastasis through activation of Smad2/3

      Tldr is basically that creatine helps body cells (in rats) to grow. Regardless wherever they're bad (cancer) or good (muscle). At least that's how I understood that study the last time I came across it. So probably stop using creatine when you've a cancer that's growing. Or its liable to use the creatine to turbocharge it's growth

"Immunity" = "immune system activity." "Anti-tumor immunity" = "immune system activity against tumors."

  • Thankyou!! I'm sure if you have experience in the medical space this sort of thing seems obvious, but to me (non-medical), the original phrasing was so confusing. Your explanation makes sense.

I mean the summary ends with pretty clear message

> …and support the use of creatine supplementation as a strategy to augment DC-based cancer immunotherapy.

So it seems that from this research the outcome is indeed creatine = good