Comment by andsoitis

9 hours ago

> slows down the accumulation of biological aging markers in the DNA of adults with HIV

And if you don’t have HIV?

Easy to pick it up

  • Not that easy unless you really try: shared IV needles and receptive anal sex without condoms (preferably repeatedly to really prepare the tissue). And you gotta find a willing donor who is not on modern HIV drugs.

  • Not really, in most cases! I read up on the per-exposure chances of actually picking up HIV a while back[1] and was shocked at how low the risk is, especially for heterosexual men (4 in 10,000 per-exposure; insertive vaginal sex with an infected partner).

    Even in the highest-risk scenario (receptive anal sex) the risk is ~138/10,000 per exposure.

    [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6195215/

    • pregnancy would seem rare too if you only looked at the averaged per-incident chances (swings from 0% to 33%ish for about 2 days for a perfectly healthy breeding-aged couple); or if you were to compare the amount of heterosexual sexual encounters overall to the amount of pregnancies.

      but that's not really how the risk should be considered.

    • Most people have sex more than once.

      If your risk is 138/10000 per exposure and you have sex with your partner once a week for a year, that's about a 50% chance of infection overall. (Assuming the infection risks are independent, which they might not be.)

      If it's 4/10000 per exposure then that's a 2% chance of infection after a year, which for sure isn't huge but I personally would take an annual 2% risk of getting HIV quite seriously.

      (Obviously the "once a week" figure is an arbitrary choice for the sake of simplicity, and I am well aware that some people have a lot more sex than that and some have a lot less.)