Comment by metaobject

Bigloo Scheme (among others) generates C code. I've used it on a few projects to process, reformat, and visualize some meteorology data and was pleased with the result. I know some other people that used it for other scientific application development (including 3D graphics) and it performed beautifully. One of my friends used Chicken Scheme to write some interesting web scraping tools. It also has the ability to compile to C.