Comment by arthopacini

for millions of years we were constantly fasting, then we hunted and killed animals, eating their protein and fat, no carbs, we were constantly in ketosis

We recently begun eating carbs, And very very recently started eating tons of processed carbs (because now we got the tech)

We are rarely in ketosis, and because of high carbs/sugar consumption, we start developing insulin resistance. (the idea is simple, we create resistance for most drugs/substances we take, be it anti depressants, caffeine, nicotine and so on.. the same happens with insulin. each time you eat too much sugar, your pancreas needs to issue insulin, so your cells can absorb more sugar. they start being resistant to it, so your pancreas need to work stronger and issue more and more insulin)

insulin is oxidative and inflammatory. we simply weren't built to regulate our blood sugar levels down (we are only equipped with insulin to do so), we are more well equipped to spike glucose levels up (gluconeogenesis, glucagon, cortisol and so on...)

because we are rarely in ketosis, we rarely get into the autophagy state (which is the auto-recycling cell system). so our cells multiply and the most error prone structure is the mitochondria.

mitochondria can make energy either from glucose or fat(keto bodies). it will always prefer glucose, only fallback to keto bodies (fat) when there is no glucose available. the synthesis of ATP (energy) from keto bodies will need oxygen as input, and will yield water as output. if we have inflammation, there is no oxygen (that's why severe chronic inflammation can lead to cancer), also that's why we usually use ice when we hurt ourselves, that place is inflamed, and by putting ice on it, it will change temperature (which changes pressure) and boosts blood circulation, blood carries oxygen, oxygen helps with inflammation.

a cancer cell, with a problematic mitochondria, will not be able to metabolize fat(keto bodies), because it has a problematic carburetor. fact is that the PET scans look for high glucose metabolism places in your body, because the cancer cells are starving for glucose.

the cell DNA is like ECC memory, it has self correction, but the mitochondria lacks the self correction, so it's way simpler to have it gone bad.

every single day we are having tons of cancer cells in our bodies, which self destruct or are detected and destroyed by our immune system.

the Middle East is the region in the world with the least cancer rate in the globe, yet they are one of the top consumers of sugar. but in islam they do the ramadan, in which for one month they make intermittent fasting basically, which boosts autophagy.

anyway... do healthy keto, boost autophagy, avoid ultra processed foods.

actually, I will extend this a little bit more... if you want to enter in keto...

go to the grocery store and buy this:

- meat (ground meat is fine and easy to prepare) - eggs (the most fresh ones if possible) - broccoli - butter or extra virgin olive oil

the portions will depend on your body type and so on.. but you would make meat and eggs on either butter and extra virgin olive oil, salt and pepper, and steamed broccoli. in my case it was 250g of ground meat, 4-5 eggs and one whole broccoli.

you must eat the broccoli first (it's fiber, you can't actually use it, the bacteria in your stomach does, it will make them very happy). if you eat meat+eggs first, you will feel full and will not be able to eat the broccoli, if you eat broccoli first, you will not feel full at all. use salt and pepper and olive oil.

eat the whole broccoli, that's like an ETF of micronutrients, it's very diversified!

then eat eggs+meat no problem...

you gonna feel very very full... do not eat any sugar/carbs.. it can take up to 3 days for entering in ketosis..

you can eat 2 to 3 times a day, eat only when you are genuinely hungry (your hunger will change drastically on how it's built over time)

then slowly entering in ketosis..

the rationale is that you need to cut off the garbage.. meat has high quality protein and fat, so does eggs (an egg has everything needed to begin a freaking life, fun fact: no carbs/sugar in it...)

and the broccoli has micronutrients and make your gut bacteria happy.

the quality of those 3 foods will depend on some things..

for the broccoli, it's the soil... is it contaminated or not? where did it grow?

for the eggs, is the chicken healthy? did she get sun? did she eat insects, worms, or just genetic modified ration?

same for the cattle...

but you are limiting a lot the potential contaminations sources..